Mendelian Randomization (MR) is a widely embraced approach to assess causality in epidemiological studies. Two-stage least squares (2SLS) method is a predominant technique in MR analysis. However. it can lead to biased estimates when instrumental variables (IVs) are weak. https://www.diegojavierfares.com/amazing-price-Rubbermaid-8-Gallon-Plastic-Home-Office-Wastebasket-Trash-Can-with-Liner-Lock-p12316-big-deal/