There exists a release of norepinephrine through the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors in the dorsal horn to decrease afferent pain transmission and make analgesia. Hence, medication like clonidine that target alpha-2 receptors can impact the transmission of agony. Could be offered as monotherapy or as https://battistai859fmu4.corpfinwiki.com/user