Epidural clonidine used as an adjunct to nearby anesthetics has a few different mechanisms of action. 1st, the stimulation of alpha-2-receptors in the dorsal horn minimizes agony transmission. Next, clonidine could potentially cause regional vasoconstriction that limits vascular elimination of regional epidural anesthetics. Clonidine is a protracted-time period medication. https://elliotpmfvo.articlesblogger.com/54850368/onolidine-an-overview