44 Moreover, anergic cells Typically keep an increased susceptibility to apoptosis Unless of course anti-apoptotic proteins including BCL2 are overexpressed, as is the case for CLL cells.45 In fact, most key therapeutic developments happening in the final decade are relevant to the inhibition of BCR and BCL2-mediated signaling. Di segmen https://shirina577kli5.iamthewiki.com/user