Additionally, PP242 was revealed to induce ERK activation in MM cell lines in addition to primary cells, which was not correlated with S6K inhibition nor was it prevented by PI3K inhibition. ERK activation could be prevented by MEK inhibitors and it is related to concurrent stimulation of Raf kinase activity https://gregoryzvnfw.blog2news.com/29068983/detailed-notes-on-as1842856